How long is the continuation phase of treatment for standard active tuberculosis infection?

The continuation phase of treatment for standard active tuberculosis (TB) infection typically lasts for 4 to 7 months, but the most common regimen used follows a total treatment course duration of 6 months. This consists of an initial intensive phase lasting 2 months, during which a combination of first-line anti-TB agents, such as isoniazid, rifampin, pyrazinamide, and ethambutol, is administered. After this phase, the continuation phase includes a sustained use of isoniazid and rifampin over the remaining 4 months, completing a standard 6-month treatment regimen.

This continuation phase is essential because it helps eliminate any remaining bacteria that might continue to cause infection if not properly treated. Adhering to the full 6-month treatment can significantly reduce the risk of developing drug-resistant TB and improve overall treatment outcomes. Thus, the correct duration of the continuation phase is best understood as part of this broader context of TB management, highlighting its role in ensuring complete recovery from the infection.