In the treatment of cirrhosis, what is used to manage symptoms of pruritus?

Cholestyramine is the correct choice for managing symptoms of pruritus in patients with cirrhosis. Pruritus, or itching, in these patients is often due to the accumulation of bile salts in the bloodstream, a consequence of cholestasis associated with liver dysfunction. Cholestyramine, a bile acid sequestrant, works by binding bile acids in the intestine, which reduces their reabsorption and consequently lowers their levels in the bloodstream. This action can alleviate the pruritus associated with cholestatic liver diseases, including cirrhosis.

Lactulose is primarily used to treat hepatic encephalopathy by reducing ammonia levels, and while it plays a vital role in liver management, it does not address pruritus directly. Paracentesis is a procedure performed to remove excess fluid from the abdomen in cases of ascites but does not target pruritus. Diuretics can help manage fluid retention in cirrhosis but have no impact on the itching sensation. Therefore, cholestyramine stands out as the most effective option for relieving pruritus in cirrhosis.