What is a significant side effect of Rifampin, a medication used to treat tuberculosis?

Rifampin is well-known for causing a significant side effect of orange-colored secretions, including urine, sweat, saliva, and tears. This occurs due to the drug’s ability to induce colored metabolites that are excreted from the body, leading to the noticeable discoloration. This effect is mostly harmless and serves as a visual reminder for patients taking the medication.

While other medications can cause various side effects, the association of Rifampin with the orange discoloration is a distinctive characteristic that helps patients and healthcare providers identify the drug's effects. Understanding this side effect is essential for patient education, as it can prevent unnecessary concern about the changes in bodily secretions that accompany Rifampin therapy.