Which condition can lead to biliary strictures, resulting in extrahepatic jaundice?

The condition that can lead to biliary strictures and result in extrahepatic jaundice is malignant tumors. These tumors, particularly those located in the head of the pancreas or involving bile ducts, can cause obstruction of the bile duct system. When the bile duct is obstructed, bile cannot flow from the liver to the intestines, leading to the accumulation of bile in the liver and subsequent jaundice, which is characterized by a yellowing of the skin and eyes due to elevated bilirubin levels in the bloodstream.

Malignant tumors can directly invade or compress the bile ducts, causing strictures that impede bile flow. This mechanical obstruction is a primary mechanism by which tumors can lead to jaundice. In contrast, while other conditions may have impacts on the gastrointestinal tract or liver function, they do not typically result in the same direct obstruction of the biliary system that leads to extrahepatic jaundice. For example, chronic pancreatitis can cause discomfort and complications in the pancreas, but its direct link to biliary strictures is not as pronounced as with malignancies. Similarly, gastric bypass surgery may affect nutrient absorption and lead to complications, but it does not typically create strictures in the biliary system. Hypertension, while a significant health concern,