Which electrolyte imbalance is commonly associated with Guillain-Barré Syndrome?

Guillain-Barré Syndrome (GBS) is an acute inflammatory condition characterized by rapid-onset muscle weakness, often triggered by an infection. One of the important aspects of GBS is its potential impact on the autonomic nervous system, which can lead to various complications, including electrolyte imbalances.

Hyponatremia, which is a decreased level of sodium in the blood, is commonly associated with GBS. In this condition, patients may experience autonomic dysfunction, leading to issues such as inappropriate secretion of antidiuretic hormone (SIADH) or fluid retention, which can dilute sodium levels in the serum. The association of GBS with hyponatremia highlights the autonomic dysregulation and the need for careful monitoring and management of electrolytes in affected patients.

The other choices—hyperkalemia, hypocalcemia, and hypokalemia—are not typically seen as primary concerns or associated imbalances in Guillain-Barré Syndrome. Each of these imbalances has its own set of causes and conditions that are more directly related to specific disorders or complications, making hyponatremia the most relevant electrolyte disturbance in the context of this syndrome.