Which medication is administered as an antidote for heparin toxicity?

Protamine sulfate is the antidote specifically used for heparin toxicity. Its mechanism of action involves binding to heparin molecules, neutralizing their anticoagulant effects. When a patient experiences bleeding or other complications from heparin, administering protamine sulfate can reverse these effects and restore normal hemostasis.

In clinical practice, this situation is particularly relevant for patients undergoing procedures where rapid reversal of anticoagulation is necessary. The dose of protamine sulfate is usually determined based on the amount of heparin that has been administered, emphasizing the importance of close monitoring and individualized dosing in managing heparin toxicity.

Other options mentioned do not serve the purpose of reversing heparin's effects. For example, vitamin K is an antidote for warfarin toxicity, not heparin. Clopidogrel is an antiplatelet medication, and enoxaparin is a low molecular weight heparin that carries a similar risk of bleeding as unfractionated heparin. Thus, these alternatives do not address heparin toxicity directly and are not suitable for reversal in that specific context.