Which rapid-acting insulin is commonly used at mealtimes?

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Insulin aspart is a rapid-acting insulin that is specifically designed for mealtime use. It has a quick onset of action, typically starting to lower blood glucose levels within 10 to 20 minutes after administration, peaking around 1 to 3 hours, and lasting for a duration of about 3 to 5 hours. This profile makes it ideal for controlling postprandial blood sugar levels, which is essential for patients managing diabetes during meals.

In contrast, regular insulin, often referred to as short-acting insulin, while also usable for meals, has a slower onset and is typically not the first choice for mealtime management due to its longer duration of action and delayed peak time. NPH insulin, an intermediate-acting insulin, has an even longer duration and is not suitable for managing blood sugar spike right after meals. Insulin detemir, a long-acting insulin, is predominantly used for basal insulin coverage rather than for the acute control required with meals. Thus, insulin aspart is clearly the preferred choice for managing blood glucose at mealtime due to its rapid onset and effectiveness in mimicking the normal insulin response to food intake.

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