Which sign is indicative of hypocalcemia?

Chvostek's sign is a classic indicator of hypocalcemia and involves a twitching of the facial muscles in response to tapping on the facial nerve, which is located just anterior to the ear. This response occurs due to increased neuromuscular excitability that is characteristic of low calcium levels in the blood. In clinical practice, the presence of Chvostek's sign can help in the early identification of hypocalcemia, allowing for timely intervention and management.

The other signs listed are associated with different neurological conditions: Brudzinski's sign and Kernig's sign are suggestive of meningitis, indicating irritation of the meninges. Hoffmann's sign is used to assess for upper motor neuron lesions, specifically in conditions such as cervical myelopathy. Understanding the different signs and their specific associations is crucial in differentiating between various clinical conditions and arriving at an accurate diagnosis.