Which type of influenza is known to be associated with more severe outbreaks?

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Influenza A is known to be associated with more severe outbreaks primarily due to its ability to undergo frequent antigenic shifts and drifts, which allow it to evade the immune system. This adaptability leads to significant changes in the virus that can result in widespread illness, as the population may have little to no pre-existing immunity to new strains. Additionally, Influenza A viruses are capable of infecting not only humans but also a variety of other species, including birds and swine, which can serve as reservoirs for the virus and facilitate the emergence of new, more virulent strains.

The severity of outbreaks associated with Influenza A is evidenced by historical pandemics, such as the 1918 influenza pandemic and the more recent H1N1 outbreak in 2009. In contrast, Influenza B typically causes less severe illness and generally leads to localized epidemics rather than global pandemics. Influenza C tends to cause mild respiratory illness and is not associated with severe outbreaks. Influenza D primarily affects cattle and does not typically infect humans, making it irrelevant in the context of human influenza outbreaks. Therefore, Influenza A stands out in terms of its potential for significant public health impact.

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